I was really hesitant at first to buy this product, due to it being pricey. But I'm really glad I gave it a try! I had been struggling with perioral dermatitis on my face for about 6-8 months. I went to the dermatologist and was prescribed antibiotics for 3 months, which only seemed to make my face worse. I gave up on the meds and did some researching online. I read that although doctors don't know exactly what causes perioral dermatitis, some suggest it might be linked to candida overgrowth and leaky gut issues. So I started taking a good/expensive probiotic (Garden of Life 100 billion) and added this Thorne perma clear to my daily regimen. I can say that now after finishing this first Thorne bottle, my face is clear again. I'm also experiencing less bloating, which I didn't even realize I had before. Stomach is so much flatter! So for me, the price is well worth the results. Read more

After some expensive trips to the vet hospital, exploratory surgery, and other tests, it was determined our 5yr old cat's triaditus was triggered by something similar to IBS. Our vet recommended we try Perma-Clear. 5hrs after his first dose, he had the first normal stool in 3yrs! A profound change, and it's been 4mos now and his mood, activity level, and body weight has improved to the point he's like a kitten now. Gone is cleaning his fur of poop, gone is low energy, gone is puking, and most importantly, gone is the every 3mos bout of triaditus which nearly kills him each time (care for this is supportive...antibiotics and subcutaneous fluids twice a day). If this works half as well for humans as it did for our can, you will be thrilled.Update: We just passed the 9mos point, and the cat's IBS and pancreas issues appear to be gone (it would have happened a few months ago if this stuff didn't work). He still gets one dose each night, and we ain't stopping. Read more

I've had crazy stomach issues for 2 years after a dose of the strongest antibiotics of my life. Some days I digest food well, other days there's a war in my stomach.I started using this in combination with Restore for Gut Health, and all of my problems went away in 2 days. Each day my stomach gets better and better. Crazy how fast this worked!! I feel like I almost have a normal stomach again. Also does wonders for BM.I take this and Restore on an empty stomach 3x a day. The bottle says 3 pills 2x a day, but I find 3 pills 3x a day much better. Read more

My doctor prescribed this for me and trusts the maker for high quality. Cheaper on Amazon than in her office. Read more

Great probiotic! Read more

GREAT Read more

good Read more

I have suffer with inflammation in all aspects of my body which includes gut issues. This really balanced me out, gave me my energy back. Thorne was sold to me originally 20 years ago by my nutritionist and I go back to it when I am not feeling well, usually from too much sugar and processed food for too long. Always makes me feel better. Read more

This is the best product for my needs. Thank you Read more