I decided to try this as recent studies have shown something quite remarkable about how levels of this substance in our blood correlate with the incidence and severity of all types of depression. In mice studies, not only did they find that the severity of depression was directly related to the severity of deficiency of this nutrient, but that administering this nutrient resulted in a complete reversal of depression related behaviors. In humans, it has been shown that there is a direct correlation between the severity of deficiency and severity of depression, with the lowest levels being associated with depression unresponsive to medicine. I expect more studies to be forth coming.Like a lot of people, I find the holidays are a time when many people experience some level of depression. Living in the northern hemisphere doesn't help for many either, causing seasonal affective disorder (SAD). I'm no exception. But given there is such a strong correlation between deficiency of this nutrient and all forms of depression, I thought I would give it a try.Within a couple days I definitely noticed a difference. After several days I felt so much better I started forgetting to take it. A couple days of that and I found myself just feeling blah, unmotivated, despondent. I took a dose, and a couple hours later was feeling incredibly better.I recommend people look into the recent research and decide for themselves. I can say for me it's definitely helping. Read more

I tried acetyl l-carnitine after reading that it enhanced the effects of r lipoic acid which I was already taking. R lipoic Acid is a powerful antioxidant, “‘the antioxidant’s antioxidant.’ This remarkable fatty acid is not only a potent antioxidant in its own right but serves as the linchpin in the body’s antioxidant network by regenerating the other major antioxidants. By far the most important of these...is glutathione (which cannot be taken as a supplement because it’s destroyed in the digestive tract). Glutathione is the mitochondria’s number one defender, and lipoic acid is glutathione’s number one regenerator.”The Linus Pauling Institute in Oregon cites “numerous studies on the use of lipoic acid as therapy for diseases associated with impaired energy utilization or increased oxidative stress, such as type 2 diabetes and heart disease. They emphasize that there is a significant age-related mitochondrial decay in heart cells and that either ALC or lipoic acid can ameliorate this decay independently. Because of the complementary nature of the effects of these two agents on mitochondria, however, some scientists—most notably Bruce Ames—recommend that they be taken together.” Quote from an article on a website called life-enhancement.com.I tried this brand of ALC after trying Doctors Best. I feel like this one is more effective as far as mood enhancement and short term memory. I’m 57 and more concerned with brain health these days. Read more

I first stumbled upon this brand by accident, thinking they were another company of acetyl-l-carnitine (ALCAR) suppliers I had purchased from previously. In any case this is a high quality product, and it's just what I was looking for-- even slightly better priced than the other supplier I had purchased from previously. I wanted to get as much ALCAR as I could in as few capsules as possible, with no other extra ingredients. I also wanted to make sure the product was genuine, so I opened up a few capsules and tasted the product myself and, sure enough, the characteristic citrus flavor of ALCAR came through. Not only that, but I can feel its effects. It's great for the brain and all sorts of other health benefits can be enjoyed from this supplement-- so I'm glad I found a supplier that is trustworthy at a very good price. It's great for vegetarians like myself who wouldn't get very much of this amino acid naturally from our diets. It's also great for weight lifters and people who are into nootropics. Read more

Ordered for my husband, this supplement was recommended to us by our fertility doctor. Was delivered quickly, but the capsules were stuffed into the bottle, all the way to the top, which I would normally be fine with, but it caused all of the capsules to burst open and spill sticky, white powder all over the other capsules inside the bottle. They became a huge clump in the bottle, impossible to get out without breaking them. Total waste of money and we can’t return them due to opening them. We will go buy this supplement in store somewhere. Just sucks we’re out $20. Read more

It’s pretty simple ladies and gentlemen. Get the product you need here (if you’re looking for Acetyl-L-Carnitine not to be confused with the less expensive L-Carnitine) at a better value than from other manufacturers. Skip the fancy bottles and all the reviews and go with the startup company trying to grow their business. I’m buying several supplements from them now and had zero regrets. Just appreciate the lightened hit to the wallet. I can always appreciate that. Take care. Read more

Even the replacement bottle had the same issues. Smaller bottle than previously and capsules appear smaller. MG the same so less filler?Capsules were packed in tight to the point of some capsules being damaged (some split open at the ends)Changing vendors - No response yet from vendor in spite of direct input on their web page 3 days ago.Replacement bottle was just as bad and I changed brands.In the meantime I have been using up the capsules from the prior purchase and am finding broken capsules.I have discontinued using this brand for any supplements. Read more

I noticed a change in both my wife and myself. It has improved our memory and improved our quality of life. We were both sceptical but I'm convinced it works. This is our third reorder. Read more

I have low thyroid function and heart problems. My hands and feet are ALWAYS cold. When others are wearing regular clothing I am layered for warmth. The benefits of this supplement are accumulative. If you forget to take it one time it is okay. I am WARM like a normal person again. I am not sure how this works but read about this supplement and decided to give it a try and I will be purchasing it again and again. Read more

I definitely recommend this, dont think about the price. As i am consuming 500mg 1 capsule a day it's 200 days stack which is more than 6 months.. Read more

Placebo or not. This seems to work for me . Read more